DVL2 Antibody

Size

100ul

Clone Number

Aliases

Dishevelled 2 (homologous to Drosophila dsh) antibody; Dishevelled dsh homolog 2 antibody; dishevelled segment polarity protein 2 antibody; Dishevelled-2 antibody; Dishevelled2 antibody; DSH homolog 2 antibody; DVL 2 antibody; Dvl2 antibody; DVL2_HUMAN antibody; Segment polarity protein dishevelled homolog DVL 2 antibody; Segment polarity protein dishevelled homolog DVL-2 antibody; Segment polarity protein dishevelled homolog DVL2 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O14641

Immunogen

Recombinant Human Segment polarity protein dishevelled homolog DVL-2 protein (1-240AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200

Background

Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes .

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

DVL2

Research Areas

Stem cells