DTX3 Antibody

Size

100ul

Clone Number

Aliases

Deltex3 antibody; Dtx3 antibody; DTX3_HUMAN antibody; Protein deltex 3 antibody; Protein deltex-3 antibody; RING finger protein 154 antibody; RNF154 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q8N9I9

Immunogen

Recombinant Human Probable E3 ubiquitin-protein ligase DTX3 protein (90-347AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context (By similarity). Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

DTX3

Research Areas

Epigenetics and Nuclear Signaling; Stem cells