Dsg2 Polyclonal Antibody

Ab type

Primary antibody

Background

DSG2 encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. DSG2 is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human DSG2. AA range:401-450

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

122294

synonyms

DSG2; CDHF5; Desmoglein-2; Cadherin family member 5; HDGC