DR1 Antibody

Size

100ul

Clone Number

Aliases

Down regulator of transcription 1 antibody; Down regulator of transcription 1 TBP binding antibody; Down-regulator of transcription 1 antibody; down-regulator of transcription 1; TBP-binding (negative cofactor 2) antibody; DR 1 antibody; Dr1 antibody; Dr1 protein antibody; NC 2 antibody; NC2 antibody; NC2 beta antibody; NC2-beta antibody; NC2B_HUMAN antibody; Negative co factor 2 antibody; Negative cofactor 2 antibody; Negative cofactor 2 beta antibody; Negative cofactor 2-beta antibody; Protein Dr1 antibody; TATA binding protein associated phosphoprotein antibody; TATA box/binding protein associated phosphoprotein DR1 antibody; TATA-binding protein-associated phosphoprotein antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q01658

Immunogen

Recombinant Human Protein Dr1 protein (1-176AA)

Raised in

Rabbit

Species Reactivity

Human, Rat

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background

The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

DR1

Research Areas

Epigenetics and Nuclear Signaling