dps Antibody

Size

100ug

Clone Number

Aliases

dpsDNA protection during starvation protein antibody; EC 1.16.-.- antibody

Immunogen Species

Mycobacterium smegmatis

UniProt ID

P0C558

Immunogen

Recombinant Mycobacterium smegmatis DNA protection during starvation protein (1-183AA)

Raised in

Rabbit

Species Reactivity

Mycobacterium smegmatis

Tested Applications

ELISA, WB; Recommended dilution: WB:1:500-1:5000

Background

Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction (By similarity). It protects DNA from hydroxyl radical-mediated cleavage. Binds DNA with no apparent sequence specificity without self-aggregation nor promotion of DNA condensation. Is unable to protect DNA from DNase-mediated cleavage.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

dps

Research Areas

Others