DPH7 Antibody

Size

100ug

Clone Number

Aliases

C9orf112 antibody; Diphthamide biosynthesis 7 antibody; DPH7 antibody; FLJ90634 antibody; OTTHUMP00000022705 antibody; RP11-48C7.3 antibody; RRT2 antibody; WD repeat domain 85 antibody; WD repeat-containing protein 85 antibody; wdr85 antibody; WDR85_HUMAN antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9BTV6

Immunogen

Recombinant Human Diphthine methyltransferase protein (210-325AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Catalyzes the demethylation of diphthine methyl ester to form diphthine, an intermediate diphthamide biosynthesis, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2) which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

DPH7

Research Areas

Cancer; Metabolism; Signal transduction