DOK3 Antibody

Size

100ug

Clone Number

Aliases

Docking protein 3 antibody; DOK 3 antibody; DOK Like Protein antibody; Dok3 antibody; DOK3_HUMAN antibody; DOKL Pending antibody; Downstream of tyrosine kinase 3 antibody; p62 DOK Like Protein antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q7L591

Immunogen

Recombinant Human Docking protein 3 protein (1-146AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200

Background

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

DOK3

Research Areas

Cancer; Signal transduction