Dok-2(Phospho Tyr345) Polyclonal Antibody

Ab type

Primary antibody

Background

The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized phospho-peptide around the phosphorylation site of human Dok-2 (phospho Tyr345)

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

45379

synonyms

Docking protein 2; DOK2; Docking protein 2; Downstream of tyrosine kinase 2; p56;dok-2