DOCK4 Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This gene is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain| a DHR-2 (CZH-2) domain and an SH3 domain. This membrane-associated| cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian| prostate| glioma| and colorectal cancers. Alternatively spliced variants which encode different protein isoforms have been described| but only one has been fully characterized.

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human DOCK4

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

216260

synonyms

DOCK4