DOCK 180 Polyclonal Antibody

Ab type

Primary antibody

Background

DOCK1 encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. Dedicator of cytokinesis protein 1 regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in multiple transcript variants.

Reactivity

Human;Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human DOCK1. AA range:1661-1710

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

215376

synonyms

DOCK1; Dedicator of cytokinesis protein 1; 180 kDa protein downstream of CRK; DOCK180