DNA pol Epsilon A Polyclonal Antibody

Ab type

Primary antibody

Background

POLE (DNA polymerase epsilon, catalytic subunit) encodes the catalytic subunit of DNA polymerase epsilon. The enzyme is involved in DNA repair and chromosomal DNA replication. Mutations in POLE have been associated with colorectal cancer 12 and facial dysmorphism, immunodeficiency, livedo, and short stature.

Reactivity

Human;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human POLE1. AA range:1261-1310

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

261518

synonyms

POLE; POLE1; DNA polymerase epsilon catalytic subunit A; DNA polymerase II subunit A