DNA pol Beta Polyclonal Antibody

Ab type

Primary antibody

Background

DNA polymerase beta encoded by POLB is a DNA polymerase involved in base excision and repair, also called gap-filling DNA synthesis. The encoded protein, acting as a monomer, is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage. Several transcript variants of POLB exist, but the full-length nature of only one has been described to date.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human DNA Polymerase beta. AA range:286-335

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

38178

synonyms

POLB; DNA polymerase beta