DNA pol beta (Acetyl Lys72) Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

Catalytic activity:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).|cofactor:Binds 2 magnesium ions per subunit.|Residues 239-252 form a flexible loop which appears to affect the polymerase fidelity.|Repair polymerase. Conducts "gap-filling" DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.|PTM:Methylation by PRMT6 stimulates the polymerase activity by enhancing DNA binding and processivity.|Belongs to the DNA polymerase type-X family.|subunit:Monomer.|

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human DNA pol β (Acetyl Lys72)

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

36850

synonyms

DNA pol β ;Acetyl Lys72; DNA polymerase beta; EC 2.7.7.7; EC 4.2.99.-