DNA Ligase III Polyclonal Antibody

Ab type

Primary antibody

Background

LIG3 is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. DNA ligase 3 encoded by LIG3 is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from DNA Ligase III . at AA range: 110-190

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

102691

synonyms

LIG3; DNA ligase 3; DNA ligase III; Polydeoxyribonucleotide synthase [ATP] 3