DMP1 Antibody

Size

100ul

Clone Number

Aliases

DMP1 antibody; Dentin matrix acidic phosphoprotein 1 antibody; DMP-1 antibody; Dentin matrix protein 1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q13316

Immunogen

Recombinant Human Dentin matrix acidic phosphoprotein 1 protein (254-513AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

May have a dual function during osteoblast differentiation. In the nucleus of undifferentiated osteoblasts, unphosphorylated form acts as a transcriptional component for activation of osteoblast-specific genes like osteocalcin. During the osteoblast to osteocyte transition phase it is phosphorylated and exported into the extracellular matrix, where it regulates nucleation of hydroxyapatite.

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

DMP1

Research Areas

Developmental biology; Signal transduction; Stem cells