DLX1 Antibody

Size

100ug

Clone Number

Aliases

DII B antibody; Distal less homeo box 1 antibody; Distal less homeobox 1 antibody; Distal-less homeobox gene 1a antibody; Dlx 1 antibody; Dlx antibody; Dlx1 antibody; Dlx1 distal-less homeobox 1 antibody; DLX1_HUMAN antibody; Homeo box protein DLX1 antibody; Homeobox protein DLX 1 antibody; Homeobox protein DLX-1 antibody; Homeobox protein Dlx1a antibody; Homeodomain transcription factor DLX1 antibody; MGC189409 antibody; OTTHUMP00000082494 antibody; OTTHUMP00000082497 antibody; OTTMUSP00000014202 antibody; RP23-419H3.3 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P56177

Immunogen

Recombinant Human Homeobox protein DLX-1 protein (8-114AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IF; Recommended dilution: IF:1:50-1:200

Background

Plays a role as a transcriptional activator or repressor (PubMed:14671321). Inhibits several cytokine signaling pathways, such as TGFB1, activin-A/INHBA and BMP4 by interfering with the transcriptional stimulatory activity of transcription factors, such as MSX2, FAST2, SMAD2 and SMAD3 during hematopoietic cell differentiation (PubMed:14671321). Plays a role in terminal differentiation of interneurons, such as amacrine and bipolar cells in the developing retina (By similarity). Likely to play a regulatory role in the development of the ventral forebrain (By similarity). May play a role in craniofacial patterning and morphogenesis and may be involved in the early development of diencephalic subdivisions (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

DLX1

Research Areas

Epigenetics and Nuclear Signaling; Neuroscience; Stem cells