DLL4 Antibody

Size

100ug

Clone Number

Aliases

AOS6 antibody; Delta 4 antibody; delta 4 precursor antibody; Delta ligand 4 antibody; delta ligand 4 precursor antibody; Delta like 4 antibody; Delta like 4 homolog antibody; Delta like 4 protein antibody; Delta like canonical Notch ligand 4 antibody; Delta like protein 4 antibody; Delta-like 4 (Drosophila) antibody; Delta-like protein 4 antibody; Delta4 antibody; DLL 4 antibody; Dll4 antibody; DLL4_HUMAN antibody; Drosophila Delta homolog 4 antibody; hdelta2 antibody; Homeobox protein DLL-4 antibody; MGC126344 antibody; Notch ligand delta 2 antibody; Notch ligand DLL4 antibody; Notch ligand DLL4 precursor antibody; XDLL-4 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9NR61

Immunogen

Recombinant Human Delta-like protein 4 protein (44-345AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IF; Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200

Background

Involved in the Notch signaling pathway as Notch ligand (PubMed:11134954). Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting (PubMed:20616313). Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types (By similarity). During spinal cord neurogenesis, inhibits V2a interneuron fate (PubMed:17728344).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

DLL4

Research Areas

Epigenetics and Nuclear Signaling; Neuroscience; Cell biology