DLG4 Antibody

Size

100ul

Clone Number

1H4

Aliases

Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90), DLG4, PSD95

Immunogen Species

Homo sapiens (Human)

UniProt ID

P78352

Immunogen

A synthesized peptide derived from human PSD95

Raised in

Species Reactivity

Human, Mouse, Rat

Tested Applications

ELISA, WB; Recommended dilution: WB:1:500-1:5000

Background

Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B (By similarity).

Clonality

Monoclonal

Isotype

Rabbit IgG

Purification Method

Affinity-chromatography

Conjugate

Non-conjugated

Buffer

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

DLG4

Research Areas

Neuroscience