DIAPH3 Antibody

Size

100ug

Clone Number

Aliases

AN antibody; AUNA1 antibody; Dia2 antibody; diap3 antibody; DIAP3_HUMAN antibody; DIAPH3 antibody; Diaphanous homolog 3 (Drosophila) antibody; Diaphanous homolog 3 antibody; Diaphanous related formin 3 antibody; Diaphanous; Drosophila; homolog of; 3 antibody; Diaphanous-related formin-3 antibody; DKFZp434C0931 antibody; DKFZp686A13178 antibody; DRF3 antibody; FLJ34705 antibody; mDia2 antibody; NSDAN antibody; OTTHUMP00000018480 antibody; Protein diaphanous homolog 3 antibody; RP11-26P21.1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9NSV4

Immunogen

Recombinant Human Protein diaphanous homolog 3 protein (642-849AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IF; Recommended dilution: IF:1:50-1:200

Background

Binds to GTP-bound form of Rho and to profilin. Acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. It is required for cytokinesis, stress fiber formation, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

DIAPH3

Research Areas

Signal transduction