DHFR Antibody

Size

100ul

Clone Number

9B2

Aliases

Dihydrofolate reductase (EC 1.5.1.3), DHFR

Immunogen Species

Homo sapiens (Human)

UniProt ID

P00374

Immunogen

A synthesized peptide derived from human DHFR

Raised in

Species Reactivity

Human, Mouse, Rat

Tested Applications

ELISA, WB, IHC, IP; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IP:1:200-1:1000

Background

Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA and that of DHFR2.

Clonality

Monoclonal

Isotype

Rabbit IgG

Purification Method

Affinity-chromatography

Conjugate

Non-conjugated

Buffer

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

DHFR

Research Areas

Cancer; Cell biology; Metabolism; Signal transduction