DHB8 Polyclonal Antibody

Ab type

Primary antibody

Background

In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined.

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from part region of human protein

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

Estradiol 17-beta-dehydrogenase 8 ;EC 1.1.1.62;17-beta-hydroxysteroid dehydrogenase 8;17-beta-HSD 8;3-oxoacyl-[acyl-carrier-protein] reductase;EC 1.1.1.-;Protein Ke6;Ke-6;Really interest