DGAT1 Antibody

Size

100ug

Clone Number

Aliases

ACAT related gene product 1 antibody; ACAT-related gene product 1 antibody; Acyl coenzyme A:cholesterol acyltransferase related gene 1 antibody; Acyl-CoA retinol O-fatty-acyltransferase antibody; Acyl-CoA:diacylglycerol acyltransferase antibody; ARAT antibody; ARGP1 antibody; C75990 antibody; D15Ertd23e antibody; Dgat antibody; DGAT1 antibody; DGAT1_HUMAN antibody; Diacylglycerol O acyltransferase 1 antibody; Diacylglycerol O-acyltransferase 1 antibody; DIAR7 antibody; Diglyceride acyltransferase antibody; EC 2.3.1.20 antibody; hCG_24006 antibody; MGC139064 antibody; Retinol O fatty acyltransferase antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O75907

Immunogen

Recombinant Human Diacylglycerol O-acyltransferase 1 protein (1-62AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. May be involved in VLDL (very low density lipoprotein) assembly. In liver, plays a role in esterifying exogenous fatty acids to glycerol. Functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

DGAT1

Research Areas

Cancer; Cardiovascular; Metabolism; Signal transduction