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ABCbiolab

SKU:ABCCS61807

DEUP1 Antibody

DEUP1 Antibody

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Size

100ug

Clone Number

Aliases

DEUP1 antibody; CCDC67 antibody; Deuterosome assembly protein 1 antibody; Coiled-coil domain-containing protein 67 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q05D60

Immunogen

Recombinant Human Deuterosome assembly protein 1 protein (217-292AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:200-1:500

Background

Key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells and can generate more than 100 centrioles. Probably sufficient for the specification and formation of the deuterosome inner core. Interacts with CEP152 and recruits PLK4 to activate centriole biogenesis (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

DEUP1

Research Areas

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