DEN1A Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family| such as DENND1A| function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus| connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson| 2010

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human DEN1A

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

110990

synonyms

DEN1A