DEFB126 Antibody, Biotin conjugated

Size

100ug

Clone Number

Aliases

DEFB126 antibody; C20orf8 antibody; DEFB26Beta-defensin 126 antibody; Beta-defensin 26 antibody; DEFB-26 antibody; Defensin antibody; beta 126 antibody; Epididymal secretory protein 13.2 antibody; ESP13.2 antibody; HBD26 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9BYW3

Immunogen

Recombinant Human Beta-defensin 126 protein (36-111AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Highly glycosylated atypical beta-defensin involved in several aspects of sperm function. Facilitates sperm transport in the female reproductive tract and contributes to sperm protection against immunodetection; both functions are probably implicating the negative surface charge provided by its O-linked oligosaccharides in the sperm glycocalyx. Involved in binding of sperm to oviductal epithelial cells to form a sperm reservoir until ovulation. Release from the sperm surface during capacitation and ovaluation by an elevation of oviductal fluid pH is unmasking other surface components and allows sperm to penetrate the cumulus matrix and bind to the zona pellucida of the oocyte (By similarity). In vitro has antimicrobial activity and may inhibit LPS-mediated inflammation (PubMed:19373462, PubMed:23229569).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Biotin

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

DEFB126

Research Areas

Others