DEDD Antibody

Size

100ul

Clone Number

Aliases

CASP8IP1 antibody; Death effector domain containing antibody; Death effector domain containing protein antibody; Death effector domain containing testicular molecule antibody; Death effector domain-containing protein antibody; Death effector domain-containing testicular molecule antibody; DEDD 1 antibody; dedD antibody; DEDD_HUMAN antibody; DEDD1 antibody; DEDPro 1 antibody; DEDPro1 antibody; DEFT antibody; FLDED 1 antibody; FLDED-1 antibody; FLDED1 antibody; KE 05 antibody; KE05 antibody; OTTHUMP00000031822 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O75618

Immunogen

Recombinant Human Death effector domain-containing protein (1-318AA)

Raised in

Rabbit

Species Reactivity

Human, Mouse

Tested Applications

ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background

A scaffold protein that directs CASP3 to certain substrates and facilitates their ordered degradation during apoptosis. May also play a role in mediating CASP3 cleavage of KRT18. Regulates degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3. Inhibits DNA transcription in vitro (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

DEDD

Research Areas

Cell biology