DDX21 Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

DEAD box proteins| characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD)| are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation| nuclear and mitochondrial splicing| and ribosome and spliceosome assembly. Based on their distribution patterns| some members of this family are believed to be involved in embryogenesis| spermatogenesis| and cellular growth and division. This gene encodes a DEAD box protein| which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA| folds single-stranded RNA| and may play important roles in ribosomal RNA biogenesis| RNA editing| RNA transport| and general transcription.

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human DDX21

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

86130

synonyms

DDX21