Dab1(Phospho-Tyr220) Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice| the disabled-1 gene plays a central role in brain development| directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1| and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported| but their full length nature has not been determined.

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized phosho peptide around human Dab1 (Tyr220)

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

Dab1 ;Tyr220; Disabled homolog 1