Dab1(Phospho Tyr220) Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

The PID domain specifically binds to the Asn-Pro-Xaa-Tyr(P) motif found in many tyrosine-phosphorylated proteins.|Adapter molecule functioning in neural development. May regulate SIAH1 activity.|PTM:Phosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons (By similarity). Also phosphorylated on Ser-524 independently of reelin signaling.|Contains 1 PID domain.|subunit:Associates with the SH2 domains of SRC| FYN and ABL. Interacts with DAB2IP and SIAH1 (By similarity). Interacts with LRP1.|

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human Dab1 (Phospho Tyr220)

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

64680

synonyms

Dab1 ;Phospho Tyr220; Disabled homolog 1