D4DR Polyclonal Antibody

Ab type

Primary antibody

Background

DRD4 encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in DRD4 have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. DRD4 contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human DRD4. AA range:355-404

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

48361

synonyms

DRD4; D(4) dopamine receptor; D(2C) dopamine receptor; Dopamine D4 receptor