D3DR Polyclonal Antibody

Ab type

Primary antibody

Background

DRD3 encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from D3DR . at AA range: 181-230

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

44225

synonyms

DRD3; D(3) dopamine receptor; Dopamine D3 receptor