Cytokeratin 16 Polyclonal Antibody

Ab type

Primary antibody

Background

Keratin 16 encoded by KRT16 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human Keratin 16. AA range:421-470

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

51268

synonyms

KRT16; KRT16A; Keratin; type I cytoskeletal 16; Cytokeratin-16; CK-16; Keratin-16; K16