Cytochrome b Polyclonal Antibody

Ab type

Primary antibody

Background

cofactor:Binds 2 heme groups non-covalently.|disease:Defects in MT-CYB are a rare cause of mitochondrial dysfunction underlying different myopathies. They include mitochondrial encephalomyopathy| hypertrophic cardiomyopathy (HCM)| and sporadic mitochondrial myopathy (MM). In mitochondrial myopathy| exercise intolerance is the predominant symptom. Additional features include lactic acidosis| muscle weakness and/or myoglobinuria. Defects in MTCYB are also found in cases of exercise intolerance accompanied by deafness| mental retardation| retinitis pigmentosa| cataract| growth retardation| epilepsy (multisystem disorder).|disease:Defects in MT-CYB are the cause of cardiomyopathy infantile histiocytoid (CMIH)

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human Cytochrome b. at AA range: 331-380

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

Cytochrome b; Cytochrome b; Complex III subunit 3; Complex III subunit III; Cytochrome b-c1 complex subunit 3; Ubiquinol-cytochrome-c reductase complex cytochrome b subunit