CysLTR2 Polyclonal Antibody

Ab type

Primary antibody

Background

CYSLTR1 encodes a member of the G-protein coupled receptor 1 family. Cysteinyl leukotriene receptor 1 is a receptor for cysteinyl leukotrienes, and is involved in mediating bronchoconstriction via activation of a phosphatidylinositol-calcium second messenger system. Activation of the encoded receptor results in contraction and proliferation of bronchial smooth muscle cells, eosinophil migration, and damage to the mucus layer in the lung. Upregulation of CYSLTR1 is associated with asthma and dysregulation may also be implicated in cancer. Alternative splicing results in multiple transcript variants.

Reactivity

Human

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human CLTR2. AA range:281-330

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

38541

synonyms

CYSLTR2; CYSLT2; CYSLT2R; PSEC0146; Cysteinyl leukotriene receptor 2; CysLTR2; G-protein coupled receptor GPCR21; hGPCR21; G-protein coupled receptor HG57; HPN321