CysLTR1 Polyclonal Antibody

Ab type

Primary antibody

Background

CYSLTR1 encodes a member of the G-protein coupled receptor 1 family. The cysteinyl leukotriene receptor 1 is a receptor for cysteinyl leukotrienes, and is involved in mediating bronchoconstriction via activation of a phosphatidylinositol-calcium second messenger system. Activation of the encoded receptor results in contraction and proliferation of bronchial smooth muscle cells, eosinophil migration, and damage to the mucus layer in the lung. Upregulation of this gene is associated with asthma and dysregulation may also be implicated in cancer. Alternative splicing results in multiple transcript variants.

Reactivity

Human;Monkey

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human CLTR1. AA range:131-180

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

38541

synonyms

CYSLTR1; CYSLT1; Cysteinyl leukotriene receptor 1; CysLTR1; Cysteinyl leukotriene D4 receptor; LTD4 receptor; G-protein coupled receptor HG55; HMTMF81