CYP7B1 Antibody, HRP conjugated

Size

100ug

Clone Number

Aliases

25 hydroxycholesterol 7 alpha hydroxylase antibody; 25-hydroxycholesterol 7-alpha-hydroxylase antibody; CP7B antibody; CP7B1_HUMAN antibody; Cyp7b1 antibody; Cytochrome P450 7B1 antibody; Cytochrome P450 family 7 subfamily B polypeptide 1 antibody; Cytochrome P450 subfamily VIIB polypeptide 1 antibody; Oxysterol 7-alpha-hydroxylase antibody; Oxysterol 7alpha hydroxylase antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O75881

Immunogen

Recombinant Human 25-hydroxycholesterol 7-alpha-hydroxylase protein (312-430AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA

Background

Oxysterol 7alpha-hydroxylase that mediates formation of 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC) from 25-hydroxycholesterol (PubMed:10588945). Plays a key role in cell positioning and movement in lymphoid tissues: 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC) acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

HRP

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CYP7B1

Research Areas

Cancer; Cardiovascular; Metabolism; Signal transduction