ABCbiolab
SKU:ABCCS61838
CYP7B1 Antibody, Biotin conjugated
CYP7B1 Antibody, Biotin conjugated
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Size
100ug
Clone Number
Aliases
25 hydroxycholesterol 7 alpha hydroxylase antibody; 25-hydroxycholesterol 7-alpha-hydroxylase antibody; CP7B antibody; CP7B1_HUMAN antibody; Cyp7b1 antibody; Cytochrome P450 7B1 antibody; Cytochrome P450 family 7 subfamily B polypeptide 1 antibody; Cytochrome P450 subfamily VIIB polypeptide 1 antibody; Oxysterol 7-alpha-hydroxylase antibody; Oxysterol 7alpha hydroxylase antibody
Immunogen Species
Homo sapiens (Human)
UniProt ID
O75881
Immunogen
Recombinant Human 25-hydroxycholesterol 7-alpha-hydroxylase protein (312-430AA)
Raised in
Rabbit
Species Reactivity
Human
Tested Applications
ELISA
Background
Oxysterol 7alpha-hydroxylase that mediates formation of 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC) from 25-hydroxycholesterol (PubMed:10588945). Plays a key role in cell positioning and movement in lymphoid tissues: 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC) acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells (By similarity).
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Conjugate
Biotin
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Stroage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names
CYP7B1
Research Areas
Cancer; Cardiovascular; Metabolism; Signal transduction
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