CYP2R1 Polyclonal Antibody

Ab type

Primary antibody

Background

CYP2R1 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in this gene has been associated with selective 25-hydroxyvitamin D deficiency.

Reactivity

Human;Mouse;Monkey

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from human CYP2R1. AA range:251-300

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

57359

synonyms

CYP2R1; Vitamin D 25-hydroxylase; Cytochrome P450 2R1