CYP2A6 Antibody

Size

100ug

Clone Number

Aliases

Coumarin 7 hydroxylase antibody; Coumarin 7-hydroxylase antibody; CP2A6_HUMAN antibody; CPA6 antibody; CYP2A antibody; CYP2A3 antibody; CYP2A6 antibody; CYPIIA6 antibody; Cytochrome P450 2A6 antibody; Cytochrome P450 IIA3 antibody; Cytochrome P450 subfamily IIA (phenobarbital inducible) polypeptide 6 antibody; Cytochrome P450(I) antibody; Cytochrome P450; family 2 subfamily A polypeptide 6 antibody; Flavoprotein linked monooxygenase antibody; P450C2A antibody; P450PB antibody; Xenobiotic monooxygenase antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P11509

Immunogen

Recombinant Human Cytochrome P450 2A6 protein (86-267AA)

Raised in

Rabbit

Species Reactivity

Human, Rat

Tested Applications

ELISA, WB; Recommended dilution: WB:1:500-1:5000

Background

Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Acts as a 1,4-cineole 2-exo-monooxygenase. Possesses low phenacetin O-deethylation activity.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CYP2A6

Research Areas

Cancer; Cardiovascular; Metabolism; Signal transduction