CYP26B1 Polyclonal Antibody

Ab type

Primary antibody

Background

CYP26B1 (cytochrome P450 family 26 subfamily B member 1) encodes a member of the cytochrome P450 superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein is localized to the endoplasmic reticulum, and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms. Mutations in CYP26B1 are associated with radiohumeral fusions and other skeletal and craniofacial anomalies, and increased levels of the encoded protein are associated with atherosclerotic lesions. Alternative splicing results in multiple transcript variants.

Reactivity

Human;Mouse;Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthetic peptide from human protein at AA range: 391-440

Storage Stability

-20°C for one year

Concentration

1 mg/ml

MolecularWeight_Da

57513

synonyms

CYP26B1 CYP26A2 P450RAI2