CWC22 Antibody

Size

100ug

Clone Number

Aliases

CWC22 antibody; CWC22 spliceosome associated protein homolog (S. cerevisiae) antibody; CWC22 spliceosome associated protein homolog antibody; CWC22_HUMAN antibody; EIF4GL antibody; fSAPb antibody; Functional spliceosome associated protein b antibody; KIAA1604 antibody; NCM antibody; Nucampholin homolog antibody; Pre-mRNA-splicing factor CWC22 homolog antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q9HCG8

Immunogen

Recombinant Human Pre-mRNA-splicing factor CWC22 homolog protein (360-623AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Required for pre-mRNA splicing and for exon-junction complex (EJC) assembly. Hinders EIF4A3 from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs. Through its role in EJC assembly, required for nonsense-mediated mRNA decay.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CWC22

Research Areas

Epigenetics and Nuclear Signaling