CUX1 Antibody

Size

100ul

Clone Number

Aliases

CUX1 antibody; CUTL1Homeobox protein cut-like 1 antibody; CCAAT displacement protein antibody; CDP antibody; Homeobox protein cux-1 antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

P39880

Immunogen

Recombinant Human Homeobox protein cut-like 1 protein (24-94AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IF; Recommended dilution: IF:1:50-1:200

Background

Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5\' and 3\') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer; may require the basic helix-loop-helix protein TCF4 as a coactivator (By similarity).

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CUX1

Research Areas

Epigenetics and Nuclear Signaling