CTNND1 Antibody

Size

100ug

Clone Number

Aliases

Cadherin associated Src substrate antibody; Cadherin-associated Src substrate antibody; CAS antibody; Catenin (cadherin associated protein) delta 1 antibody; Catenin delta 1 antibody; Catenin delta antibody; Catenin delta-1 antibody; CTND1_HUMAN antibody; CTNND 1 antibody; CTNND antibody; CTNND1 antibody; delta 1 Catenin antibody; KIAA0384 antibody; p120 antibody; P120 CAS antibody; p120 catenin antibody; P120 CTN antibody; p120(cas) antibody; p120(ctn) antibody; P120CAS antibody; P120CTN antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

O60716

Immunogen

Recombinant Human Catenin delta-1 protein (482-605AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background

Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). Associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CTNND1

Research Areas

Signal transduction; Stem cells