CTNNB1 Monoclonal Antibody

Size

100ul

Clone Number

Aliases

Catenin beta-1 (Beta-catenin), CTNNB1, CTNNB

Immunogen Species

Homo sapiens (Human)

UniProt ID

P35222

Immunogen

Synthesized peptide derived from human Beta-catenin

Raised in

Mouse

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background

Involved in the regulation of cell adhesion. The majority of beta-catenin is localized to the cell membrane and is part of E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton. Involved in signal transduction through the Wnt pathway. Nuclear beta-catenin it involved in transcriptional regulation by association with transcription factors of the TCF/LEF family.

Clonality

Monoclonal

Isotype

IgG2b, Kappa

Purification Method

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Conjugate

Non-conjugated

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CTNNB1

Research Areas

Signal Transduction