CTNNB1 Monoclonal Antibody

Size

Clone Number

Aliases

Immunogen Species

Human

UniProt ID

P35222

Immunogen

Recombinant Protein

Raised in

Mouse

Species Reactivity

Human,Mouse,Rat

Tested Applications

ELISA,WB,IHC;Recommended dilution:WB:1:500-1:5000,IHC:1:50-1:500

Background

The distinct peripheral cytosolic proteins, alpha, beta and gamma catenin (102, 94 and 86 kDa) are found in many tissues and bind to the conserved cytoplasmic tail domain of the cell adhesion cadherins. Catenins link E cadherin to other integral membrane or cytoplasmic proteins and are modulated by Wnt1 proto oncogene. The central core region of beta catenin is involved in mediation of cadherin catenin complex interaction with EGFR. Beta-Catenin-mediated signalling is involved at several stages of vertebrate neural development.

Clonality

Monoclonal

Isotype

IgG1

Purification Method

Antigen Affinity Purified

Conjugate

Non-conjugated

Buffer

Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form

liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CTNNB1

Research Areas

Neuroscience?Cancer?Cardiovascular;Signal transduction?Stem cells