CTDP1 Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

This gene encodes a protein which interacts with the carboxy-terminus of the RAP74 subunit of transcription initiation factor TFIIF| and functions as a phosphatase that processively dephosphorylates the C-terminus of POLR2A (a subunit of RNA polymerase II)| making it available for initiation of gene expression. Mutations in this gene are associated with congenital cataracts| facial dysmorphism and neuropathy syndrome (CCFDN). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Reactivity

Human, Mouse

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human CTDP1

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

synonyms

CTDP1; RNA polymerase II subunit A C-terminal domain phosphatase; EC 3.1.3.16; TFIIF-associating CTD phosphatase