CtBP1/2(Phospho Ser158/164) Rabbit Polyclonal Antibody

Ab type

Primary antibody

Background

cofactor:NAD. Required for efficient interaction with E1A. Cofactor binding induces a conformation change.|Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex (By similarity). Co-repressor targeting diverse transcription regulators such as GLIS2. Has dehydrogenase activity.|PTM:ADP-ribosylated; when cells are exposed to brefeldin-A (BFA).|PTM:Sumoylation on Lys-428 is promoted by the E3 SUMO-protein ligase CBX4.|PTM:The level of phosphorylation appears to be regulated during the cell cycle. Phosphorylated upon DNA damage| probably by ATM or ATR. Phosphorylation by HIPK2 on Ser-422 induces proteasomal degradation.|Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|subunit:Interacts with the C-terminus of adenovirus E1A protein| ELK3 and CTIP via their consensus motif P-X-

Reactivity

Human, Mouse, Rat

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Immunogen

Synthesized peptide derived from human CtBP1/2 (Phospho Ser158/164)

Storage Stability

-20°C for 1 year

Concentration

1 mg/ml

MolecularWeight_Da

48400

synonyms

CtBP1/2 ;Phospho Ser158/164; C-terminal-binding protein 1; CtBP1; EC 1.1.1.-