CRYZ Antibody

Size

100ug

Clone Number

Aliases

Crystallin zeta (quinone reductase) antibody; Crystallin zeta antibody; Cryz antibody; DKFZp779E0834 antibody; FLJ41475 antibody; NADPH:quinone reductase antibody; QOR_HUMAN antibody; Quinone oxidoreductase antibody; Zeta crystallin antibody; Zeta-crystallin antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q08257

Immunogen

Recombinant Human Quinone oxidoreductase protein (47-109AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC; Recommended dilution: IHC:1:200-1:500

Background

Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3\'-UTR of target mRNA species. Enhances the stability of mRNA coding for BCL2. NADPH binding interferes with mRNA binding.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CRYZ

Research Areas

Epigenetics and Nuclear Signaling; Neuroscience; Metabolism; Signal transduction