CRYM Antibody

Size

100ug

Clone Number

Aliases

CRYM antibody; CRYM_HUMAN antibody; Crystallin mu antibody; DFNA 40 antibody; DFNA40 antibody; Ketimine reductase antibody; Mu crystallin homolog antibody; Mu-crystallin homolog antibody; NADP regulated thyroid hormone binding protein antibody; NADP-regulated thyroid-hormone-binding protein antibody; OTTHUMP00000115878 antibody; THBP antibody; Thiomorpholine carboxylate dehydrogenase antibody

Immunogen Species

Homo sapiens (Human)

UniProt ID

Q14894

Immunogen

Recombinant Human Ketimine reductase mu-crystallin protein (169-258AA)

Raised in

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC, IF; Recommended dilution: IHC:1:500-1:1000, IF:1:50-1:200

Background

Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK). Binds thyroid hormone which is a strong reversible inhibitor. Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors.

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Conjugate

Non-conjugated

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Stroage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names

CRYM

Research Areas

Neuroscience; Signal transduction