ABCbiolab
SKU:ABCCS45116
CRX Antibody
CRX Antibody
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Size
100ul
Clone Number
Aliases
Cone rod homeobox antibody; Cone rod homeobox protein antibody; Cone rod homeobox-containing gene antibody; cone-rod homeobox antibody; Cone-rod homeobox protein antibody; CORD 2 antibody; CRD antibody; CRX antibody; CRX_HUMAN antibody; LCA 7 antibody; LCA7 antibody; Orthodenticle homeobox 3 antibody; OTX 3 antibody; OTX3 antibody
Immunogen Species
Homo sapiens (Human)
UniProt ID
O43186
Immunogen
Recombinant Human Cone-rod homeobox protein (120-285AA)
Raised in
Rabbit
Species Reactivity
Human
Tested Applications
ELISA, IHC; Recommended dilution: IHC:1:20-1:200
Background
Transcription factor that binds and transactivates the sequence 5\\\'-TAATC[CA]-3\\\' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors.
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Stroage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names
CRX
Research Areas
Epigenetics and Nuclear Signaling; Neuroscience
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